Matrix protein of cell-associated subacute sclerosing panencephalitis viruses.

Subacute Sclerosing Panencephalitis in Iran

Subacute Sclerosing Panencephalitis, immunological findings in saliva and salivary glands

Subacute Sclerosing Panencephalitis in Iran. Clinical and immunoligical characlerisation

Multiple viral mutations rather than host factors cause defective measles virus gene expression in a subacute sclerosing panencephalitis cell line.

A measles virus (MV) genome originally derived from brain cells of a subacute sclerosing panencephalitis patient expressed in IP-3-Ca cells an unstable MV matrix protein and was unable to produce virus particles. Transfection of this MV genome into other cell lines did not relieve these defects, showing that they are ultimately encoded by viral mutations. However, these defects were partially r...

Antibody response to structural proteins of measles virus in patients with natural measles and subacute sclerosing panencephalitis.

By immunoprecipitation and SDS-polyacrylamide gel electrophoresis, antibody responses to the structural proteins of measles virus were examined on patients with various forms of natural measles, atypical measles, and subacute sclerosing panencephalitis (SSPE). The serum of atypical measles most strongly reacted with four structural proteins, i.e., hemagglutinin (H), nucleocapsid (NC), fusion (F...